Fig. 5

Molecular docking analysis and visualization by BIOVIA Discovery Studio. (Blue indicates USP domain of CYLD, and chocolate color indicates ubiquitin. a indicates CYLD-ubiquitin docking complex, b indicates H-bond interactions between wild CYLD-ubiquitin dock complex, c represents H-bond interactions between mutant (H827R) CYLD-ubiquitin dock complex, d represents h-bond interactions between mutant (R830K) CYLD-ubiquitin dock complex)