Exploring molecular targets: herbal isolates in cervical cancer therapy

Genomics & Informatics

Table 1 A total of 57 genes linked to cervical cancer pathogenesis were assigned as hubs in this research

Name	Degree	Betweenness	Closeness
CDK1	171	0.051	0.440
CCNA2	151	0.024	0.426
CCNB1	145	0.025	0.423
TP53	144	0.153	0.482
TOP2A	143	0.021	0.423
BUB1	143	0.010	0.405
NCAPG	138	0.010	0.381
BUB1B	127	0.010	0.404
AURKB	125	0.009	0.402
CDC6	122	0.009	0.390
RRM2	122	0.008	0.403
CDC20	119	0.007	0.387
ASPM	118	0.006	0.374
NDC80	117	0.011	0.372
CHEK1	116	0.010	0.406
AURKA	114	0.014	0.408
EXO1	114	0.010	0.398
RFC4	110	0.007	0.397
BIRC5	107	0.031	0.419
CENPF	100	0.006	0.365
CEP55	97	0.007	0.366
PCNA	95	0.015	0.394
RAD51	94	0.013	0.396
MCM5	93	0.010	0.384
TYMS	91	0.009	0.369
STAT3	90	0.038	0.434
EGFR	89	0.085	0.447
MKI67	89	0.007	0.398
AKT1	86	0.050	0.446
HMMR	83	0.013	0.389
FOXM1	81	0.007	0.396
CTNNB1	75	0.037	0.431
MYC	73	0.025	0.437
RFC3	71	0.008	0.381
MAPK3	68	0.033	0.427
IL6	62	0.022	0.392
CCND1	62	0.016	0.430
ACTB	61	0.044	0.438
HRAS	61	0.022	0.395
CDC25C	61	0.007	0.396
ESR1	58	0.025	0.419
TNF	58	0.023	0.393
VEGFA	57	0.011	0.395
RPA3	57	0.008	0.373
STAT1	55	0.030	0.401
JUN	55	0.019	0.421
PIK3CA	55	0.014	0.391
ERBB2	53	0.025	0.423
PTEN	52	0.019	0.413
CASP3	52	0.017	0.429
MAPK1	52	0.010	0.396
CDH1	50	0.014	0.396
CD44	49	0.023	0.407
HIF1A	47	0.013	0.417
E2F1	47	0.012	0.396
MDM2	46	0.013	0.411
CDKN2A	46	0.010	0.403

ISSN: 2234-0742