Genetic diversity and natural selection analysis of VAR2CSA and vir genes: implication for vaccine development

Table 2 Insertion and deletion observed in vir 12 and vir 21 genes

	Insertion/deletion	Location	Length (Nucleotides)	Sequences	Countries
*Vir 12*	Insertion	564	3	GAA / TAT / GGA	India, Myanmar and Korea
		773	15	AAAACCTGCACCTGT	India and Myanmar
		801	15	GCAAAACCTGTAGCG	India, Myanmar and Korea
		801	30	GCAAAACCTGTAGCAGCAAAACCTGCAGAC	India and Myanmar
		921	15	GCAAAACCTGTAGCG	India
	Deletion	859	15	CGACAAAACCTGCAA	India and Myanmar
	Deletion	928	30	CTGTAGCGGCAAAACCAGCACCGGGAGAAG	India and Myanmar
*Vir 21*	Insertion	768	27	AGGGTTTCTGAAAAACCAAATATAAAT/ AAGTTATCTGAAAACCCAAATATAAAT	Myanmar
	Insertion	773	5	TTCTG/ ATCTG	Korea
	Deletion	152	3	GGC	India and Myanmar
	Deletion	786	5	TTTCT	Korea

Position number are given according to the coding sequences of Sal I reference strain accession number AAKM01000016 for vir 12 and AAKM01000003 for vir 21

ISSN: 2234-0742